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KMID : 1123920050190061656
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Korean Journal of Oriental Physiology and Pathology
2005 Volume.19 No. 6 p.1656 ~ p.1658
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Antifungal Activity of Chloroform Extract from Lepidolaena Taylorii on the Dermatophytic Fungus Trichophyton mentagrophytes
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Lee Hyun-Ok
Shin Joung-Mi
Lee Jae-Sook
Na Young-Soon
Baek Seung-Hwa
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Abstract
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The effects of chloroform extract from Lepidolaena tayiorii (L. tayiorii) on antifungal activity were investigated. The crude chloroform extract of L. tayiorii inhibited the growth of the Gram positive bacteria Bacillus subtilis ATCC 19659, (5 mm inhibition zone at ) and the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (6 mm inhibition zone at ), and cytotoxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, (/disc) and cytotoxic to BSC monkey kidney cells (@ 5 mg/mL, +++: 100% activity). We suppose that this crude chloroform extract of L. tayiorii is the strong antimicrobial and cytotoxic activities.
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KEYWORD
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Lepidolaena tayiorii, Bacillus subtilis, Trichophpon mentagrophyes, antifungal activity, P388 murine leukaemia cells, BSC monkey kidney cells
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